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Biochemists discover new strategy to combat pediatric bone cancer
Researchers at the UNC School of Medicine and UNC Lineberger Comprehensive Cancer Center are zeroing in on less toxic and more targeted strategies to combat Ewing sarcoma, an aggressive and rare pediatric cancer that develops in the bones and soft tissues.
Scientists discover a hidden brain shift that begins around age 50
Scientists discover a hidden brain shift that begins around age 50
Beginning around age 50, the brain’s memory center appears to lose many of its longtime immune cells and replace them with more inflammatory ones. This surprising shift may help explain how normal aging sets the stage for Alzheimer’s disease and dementia.
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Aberrant protein activity rewires lymphoma cells to survive BTK inhibitors, offering targe
A protein that can dial down oxidative stress in cells helps some cancers resist treatment with a widely used class of drugs called BTK inhibitors, according to a study led by investigators at Weill Cornell Medicine. The discovery points to a possible solution to the problem of B
Extreme heat: How a promising new discovery could help older adults adapt
Extreme heat: How a promising new discovery could help older adults adapt
The year 2024 marked the first time that the global average temperature exceeded the 1.5°C threshold set by the Paris Agreement. One direct consequence is more intense heat extremes, which already pose a significant threat to human health.
Tumor-secreted protein makes lung vessels leakier, promoting metastasis
Tumor-secreted protein makes lung vessels leakier, promoting metastasis
A protein secreted by common cancer types makes blood vessels leakier to allow metastatic tumors to form in the lungs, according to a study led by investigators at Weill Cornell Medicine and Memorial Sloan Kettering Cancer Center. The discovery could lead to new ways of monitorin
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Celtic learn CL opponents as Brighton discover European route
Celtic learn CL opponents as Brighton discover European route
Celtic will play Austrian champions LASK for a place in the league phase of the Champions League, while Brighton will face CFR Cluj or Tromso in the Conference League play-off round.
Celtic drawn against LASK as other Scottish sides discover opponents
Celtic drawn against LASK as other Scottish sides discover opponents
Celtic will play against Austrian champions LASK in the Champions League play-off round as four other Scottish sides discover potential Europa League and Conference League opponents
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Two new compounds could reveal hidden drivers of Alzheimer’s disease
Vanderbilt researchers created the first selective compound designed to inhibit TAOK-1, a poorly understood protein connected to Alzheimer’s disease. They also discovered a second compound that activates the entire TAOK protein family, offering scientists an unexpected new resear
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Electrocatalytic method could purify wastewater by converting pollutants into recoverable
Wastewater treatment is a critical issue for global environmental protection and public health. Researchers from The Hong Kong University of Science and Technology (HKUST) have recently achieved a major breakthrough with the discovery of a novel oxidant-free electrocatalytic mech
Human norovirus capsid shifts between two shapes, cryo-EM reveals
Human norovirus capsid shifts between two shapes, cryo-EM reveals
A research team led by Kazuyoshi Murata has discovered that virus-like particles (VLPs) of human norovirus genotype GII.3 are not structurally rigid, but can adopt two distinct conformational states, similar to those previously reported for murine norovirus.
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Diffuse inter-filament gas is likely a key fuel source for massive star formation
Researchers from Kyushu University have discovered that diffuse gas surrounding dense filaments in a nearby stellar nursery plays a much larger role in star formation than previously recognized. By tracking the movement of gas in the Monoceros R2 hub–filament system, the team fou